Context

Among the pathologies where oxidative stress plays a major role, facioscapulohumeral dystrophy (FSHD) is an extremely disabling myopathy. Patients with FSHD suffer from impaired response to oxidative stress caused in part by the abnormal expression of certain proteins. Antioxidant supplements could potentially represent an appropriate strategy to slow the progression of FSHD, on the condition that the supplements are properly adjusted and personalized.

Benefits

The prescription support mechanism for antioxidants (personalized dosage adjustment) developed in this project would make it possible to provide better care for patients with FSHD. This mechanism can also be evaluated subsequently in other disease contexts.

Applications

Improved care for patients with facioscapulohumeral dystrophy (FSHD)