HPCG
Computer system for detecting interactions between genes
Technologie commercialisée
Technology marketed by a partner
IP
- Software
ESTABLISHMENT(S)
- CNRS
- University of Montpellier
- Montpellier SupAgro
- INRA
LABORATORY(IES)
- Plant Biochemistry and Molecular Physiology (B&PMP)
- Alexander Grothendieck Institute of Montpellier (IMAG)
KEYWORDS
- Genetic variations
Co-financé par
Context
Genome-wide association studies involve searching for a statistical correlation between genetic variation and a phenotype trait. These types of studies have increased significantly over the past ten years for medical applications as well as in agronomics for plant and animal breeding. However, conventional studies only focus on the individual effects of each genetic variation, whereas interaction phenomena between several genetic variations play a major role (notion of epistasis). It is not currently possible to detect these interaction phenomena exhaustively on a genome-wide scale due to the significant increase in the number of tests generated and the required calculation time.
Benefits
This computer-based solution uses original algorithms and would make it possible to detect interaction phenomena between several genetic variations exhaustively across the entire genome in a reasonable amount of time.
Applications
- Variety and animal selection (identifying new genetic variations associated with desirable agronomic traits to optimize selection)
- Human health (personalized and/or predictive medicine)
MARKETED TECHNOLOGY I Genetic variations